Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGM2HY)

Drug Name
DCDT-2980S Drug Info
Indication
Disease Entry ICD 11 Status REF
Diffuse large B-cell lymphoma 2A81 Discontinued in Phase 2 [1]
Non-hodgkin lymphoma 2B33.5 Discontinued in Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMGM2HY

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
B-cell receptor CD22 (CD22) TTM6QSK CD22_HUMAN Not Available [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Diffuse large B-cell lymphoma
ICD Disease Classification 2A81
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
B-cell receptor CD22 (CD22) DTT CD22 1.89E-11 -0.21 -0.58
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027651)
2 Efficacy and toxicity of a CD22-targeted antibody-saporin conjugate in a xenograft model of non-Hodgkin's lymphoma. Oncoimmunology. 2012 December 1; 1(9): 1469-1475.