Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGQVF5)

Drug Name

2,5-Dideoxy-2,5-imino-D-mannitol Drug Info

Synonyms

59920-31-9; (2R,3R,4R,5R)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol; 2,5-Dihydroxymethyl-3,4-dihydroxypyrrolidine; CHEBI:4289; CHEMBL312653; NSC624987; NSC613239; 2(r),5(r)-bis(hydroxymethyl)-3(r),4(r)-dihydroxypyrrolidine; 2,5-Anhydro-2,5-imino-D-mannitol; DQQ; 2,5-dideoxy-2,5-imino-L-mannitol; NSC 624987; AC1L3YWM; AC1Q59GS; SCHEMBL466574; ZINC1492230; 2,5-Pyrrolidinedimethanol, 3,4-dihydroxy-, (2R,3R,4R,5R)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 124702
ChEBI ID: CHEBI:4289
CAS Number: CAS 59920-31-9
TTD Drug ID: DMGQVF5

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Intestinal maltase-glucoamylase (MGAM)	TTXWASR	MGA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Intestinal maltase-glucoamylase (MGAM)	DTT	MGAM	4.59E-01	-0.02	-0.24

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii. J Nat Prod. 2002 Feb;65(2):198-202.