General Information of Drug (ID: DMGYZ8D)

Drug Name
2-(4-chloro-2-cyclohexylphenoxy)acetic acid Drug Info
Synonyms
2-(4-chloro-2-cyclohexylphenoxy)acetic acid; (4-chloro-2-cyclohexylphenoxy)acetic acid; 19774-97-1; MLS002639096; CHEMBL245908; NSC26127; AC1L5KDG; AC1Q3LV0; SCHEMBL4888054; CTK7J5481; DTXSID10282496; MolPort-004-296-406; HMS3089F12; ZINC1628222; AC1Q7647; BDBM50213909; NSC-26127; AKOS000132678; NE44164; MCULE-7136939287; AS-9826; 4-chloro-2-cyclohexylphenoxy-acetic acid; SMR001548547
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
230826
CAS Number
CAS 19774-97-1
TTD Drug ID
DMGYZ8D

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin D2 receptor 2 (PTGDR2) TTQDMX5 PD2R2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Prostaglandin D2 receptor 2 (PTGDR2) DTT PTGDR2 4.436 5.954 4.217 4.641
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostaglandin D2 receptor 2 (PTGDR2) DTT PTGDR2 6.11E-02 -0.15 -0.25
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4347-50.