Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMH7CSQ)

Drug Name
Gavilimomab Drug Info
Synonyms ABX-CBL; CBL-1
Indication
Disease Entry ICD 11 Status REF
Graft-versus-host disease 4B24 Phase 2/3 [1]
Cross-matching ID
TTD Drug ID
DMH7CSQ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Basigin (BSG) TT5UJWD BASI_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Basigin (BSG) DTT BSG 6.931 9.095 8.853 7.66
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Graft-versus-host disease
ICD Disease Classification 4B24
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Basigin (BSG) DTT BSG 3.88E-09 0.88 1.35
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT00035880) Study Comparing ABX-CBL (Monoclonal Antibody) Versus Atgam in Patients With Steroid Resistant Acute Graft Versus Host Disease. U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug id 38221).