Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHBMJZ)

Drug Name

Textilinin Drug Info

Synonyms

Q-8008; Fibrinolysis inhibitor (bleeding), QRxPharma; Kunitz type serine protease inhibitor (bleeding), QRxPharma; Plasmin inhibitor (bleeding), QRxPharma

Indication

Disease Entry	ICD 11	Status	REF
Bleeding disorder	GA20-GA21	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMHBMJZ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasminogen (PLG)	TTP86E2	PLMN_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Plasminogen (PLG)	DTT	PLG	11.754	0.848	8.393	2.138

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Bleeding disorder

ICD Disease Classification

GA20-GA21

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Plasminogen (PLG)	DTT	PLG	8.61E-01	-0.01	-0.09

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Tranexamic acid in trauma: how should we use it. J Trauma Acute Care Surg. 2013 Jun;74(6):1575-86.