Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHR3ZG)

Drug Name
AP-101 Drug Info
Indication
Disease Entry ICD 11 Status REF
Ischemia 8B10-8B11 Investigative [1]
Cross-matching ID
TTD Drug ID
DMHR3ZG

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Angiopoietin 1 receptor (TEK) TT9VGXW TIE2_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Angiopoietin 1 receptor (TEK) DTT TEK 5.194 5.051 6.613 4.982
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Ischemia
ICD Disease Classification 8B10-8B11
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Angiopoietin 1 receptor (TEK) DTT TEK 4.92E-03 0.29 0.84
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1842).