Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHSORL)

Drug Name
2-(1H-pyrazol-3-yl)-1H-benzimidazole Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
763936
TTD Drug ID
DMHSORL

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aurora kinase A (AURKA) TTPS3C0 AURKA_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Aurora kinase A (AURKA) DTT AURKA 4.479 5.036 4.392 4.505
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Aurora kinase A (AURKA) DTT AURKA 9.41E-46 -1.78 -2.05
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.