Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHUD27)

Drug Name
GW-594884A Drug Info
Indication
Disease Entry ICD 11 Status REF
Obesity 5B81 Preclinical [1]
Cross-matching ID
TTD Drug ID
DMHUD27

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neuropeptide Y receptor type 5 (NPY5R) TTY6EWA NPY5R_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Neuropeptide Y receptor type 5 (NPY5R) DTT NPY5R 6.192 6.174 6.582 6.385
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Obesity
ICD Disease Classification 5B81
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Neuropeptide Y receptor type 5 (NPY5R) DTT NPY5R 7.49E-01 1.19E-02 0.03
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.