Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMI4KNB)

Drug Name

N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide Drug Info

Synonyms

CHEMBL251369; N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide; AC1MH48W; MLS001162447; SCHEMBL13148062; cid_2996093; N-[2-(morpholin-4-yl)phenyl]-5-nitrofuran-2-carboxamide; MolPort-002-305-194; HMS2967E08; ZINC4842600; STK355602; BDBM50223675; AKOS000458368; MCULE-3330873928; SMR000670465; VU0465060-1; N-(2-morpholin-4-ylphenyl)-5-nitro-2-furamide; AP-970/43481542; N-[2-(4-morpholinyl)phenyl]-5-nitro-2-furamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2996093
TTD Drug ID: DMI4KNB

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Granulocyte colony-stimulating factor receptor (G-CSF-R)	TTC70AJ	CSF3R_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Granulocyte colony-stimulating factor receptor (G-CSF-R)	DTT	CSF3R	4.087	3.406	3.17	3.322

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Granulocyte colony-stimulating factor receptor (G-CSF-R)	DTT	CSF3R	2.08E-08	0.36	0.96

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6070-4.