Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMIDGZU)

Drug Name
Telbermin Drug Info
Synonyms Telbermin (USAN/INN)
Indication
Disease Entry ICD 11 Status REF
Diabetic foot ulcer BD54 Discontinued in Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMIDGZU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vascular endothelial growth factor receptor 1 (FLT-1) TT2Q6G1 VGFR1_HUMAN Activator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Vascular endothelial growth factor receptor 1 (FLT-1) DTT FLT1 4.802 4.95 4.597 3.17
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Diabetic foot ulcer
ICD Disease Classification BD54
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vascular endothelial growth factor receptor 1 (FLT-1) DTT FLT1 4.94E-03 0.74 1.24
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Emerging drugs for diabetic foot ulcers. Expert Opin Emerg Drugs. 2006 Nov;11(4):709-24.