Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMIQOXH)

Drug Name

Apigenin-7-O-beta-D-glucuronide Drug Info

Synonyms

29741-09-1; Apigenin-7-glucuronide; Apigenin 7-O-b-glucuronide; Apigenin 7-glucuronide; apigenin-7-o-glucuronide; UNII-2CQ5KB3CH0; 2CQ5KB3CH0; CHEMBL254213; Scutellarin A; Apigenin 7-O-glucuronide; Apigenin 7-beta-glucuronide; apigenin-7-O-beta-D-glucuronide; Apigenin 7-O-beta-D-glucuronide; Apigenin-7-O-beta-D-glucuronoside; Apigenin 7-O-beta-D-glucuronopyranoside; AC1NSY61; MEGxp0_000795; SCHEMBL2400851; ACon1_001025; DTXSID10183893; MolPort-001-740-947; apigenin-7-O-betaD-glucuronic acid; HY-N1454; Apigenin 7-O-.beta.-D-glucur

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5319484
CAS Number: CAS 29741-09-1
TTD Drug ID: DMIQOXH

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aldose reductase (AKR1B1)	TTFBNVI	ALDR_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aldose reductase (AKR1B1)	DTT	AKR1B1	7.436	8.652	9.874	8.066

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aldose reductase (AKR1B1)	DTT	AKR1B1	1.08E-20	0.94	1.58

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Erigeroflavanone, a flavanone derivative from the flowers of Erigeron annuus with protein glycation and aldose reductase inhibitory activity. J Nat Prod. 2008 Apr;71(4):713-5.