Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJ108U)

Drug Name

LJP-1207 Drug Info

Synonyms

LJP-1200; LJP-1233; LJP-1586; SSAO inhibitors (inflammation); SSAO inhibitors, La Jolla; VAP-1 inhibitors, La Jolla; Vascular adhesion protein-1 inhibitors, La Jolla; Semi-carbazide-sensitive amine oxidase, La Jolla

Indication

Disease Entry	ICD 11	Status	REF
Cerebrovascular ischaemia	8B1Z	Investigative	[1]

Cross-matching ID

PubChem CID: 11615193
TTD Drug ID: DMJ108U

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Membrane copper amine oxidase (AOC3)	TT7HC21	AOC3_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Membrane copper amine oxidase (AOC3)	DTT	AOC3	7.055	8.263	6.709	7.374

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Cerebrovascular ischaemia

ICD Disease Classification

8B1Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Membrane copper amine oxidase (AOC3)	DTT	AOC3	8.36E-22	-1.03	-1.54

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).