Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJ2T7P)

Drug Name

13-Acetylphorbol Drug Info

Synonyms

Phorbol 13-acetate; 13-Acetylphorbol; Phorbol-13-acetate; Phorbol 13-monoacetate; 32752-29-7; CHEBI:45127; Phorbol13-acetate; (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9-trihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl acetate; PRB; 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one, 1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-decahydro-4a-alpha,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-hydroxymethyl-1,1,6,8-alpha-tetramethyl-, 9a-acetate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 499953
ChEBI ID: CHEBI:45127
CAS Number: CAS 32752-29-7
TTD Drug ID: DMJ2T7P

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein kinase C delta (PRKCD)	TT9WJ8U	KPCD_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Protein kinase C delta (PRKCD)	DTT	PRKCD	4.036	6.709	6	6.558

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Protein kinase C delta (PRKCD)	DTT	PRKCD	1.25E-22	0.59	0.82

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.