Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJA5Y4)

Drug Name
2-(4-benzoylpiperazin-1-yl)thiazole-5-carboxamide Drug Info
Synonyms CHEMBL568131; 2-(4-benzoylpiperazin-1-yl)thiazole-5-carboxamide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
45487374
TTD Drug ID
DMJA5Y4

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acyl-CoA desaturase (SCD) TT6RIOV ACOD_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Acyl-CoA desaturase (SCD) DTT SCD 7.165 5.49 3.271 6.434
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Acyl-CoA desaturase (SCD) DTT SCD 4.73E-01 0.2 0.54
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Thiazole analog as stearoyl-CoA desaturase 1 inhibitor. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5214-7.