Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJAPFH)

Drug Name

Asterric acid Drug Info

Synonyms

577-64-0; MLS000863583; CHEMBL469424; SMR000440714; 2-hydroxy-6-(4-hydroxy-2-methoxy-6-methoxycarbonylphenoxy)-4-methylbenzoic acid; AC1MIV9I; Asterric acid_120092; MEGxm0_000244; ZINC7778; SCHEMBL6046569; XOKVHFNTYHPEHN-UHFFFAOYSA-; cid_3080568; ACon1_001529; ACon0_000930; CTK8F7847; BDBM50711; DTXSID60206405; MolPort-001-739-484; HMS2270H17; MFCD00216131; MCULE-7550426133; NCGC00180411-01; Asterric acid, > L007432; BRD-K20637966-001-01-0

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3080568
CAS Number: CAS 577-64-0
TTD Drug ID: DMJAPFH

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Endothelin A receptor (EDNRA)	TTKRD0G	EDNRA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Endothelin A receptor (EDNRA)	DTT	EDNRA	3.776	4.505	5.121	3.536

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Endothelin A receptor (EDNRA)	DTT	EDNRA	3.19E-05	-2.69	-1.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	New chlorinated diphenyl ethers from an Aspergillus species. J Nat Prod. 2002 Jan;65(1):7-10.