Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJL8QZ)

Drug Name

(1-Amino-3-methylsulfanyl-propyl)-phosphinic acid Drug Info

Synonyms

METHIONINE PHOSPHINATE; (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID; MPJ; AC1O4QJ4; SCHEMBL4316253; ZINC29326788; DB04015; [(1R)-1-amino-3-methylsulfanylpropyl]-hydroxy-oxophosphanium; (R)-[(1R)-1-amino-3-(methylsulfanyl)propyl]phosphinic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6398483
TTD Drug ID: DMJL8QZ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aminopeptidase N (ANPEP)	TTPHMWB	AMPN_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.744	7.809	8.914	11.49

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.84E-07	-0.3	-0.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1511-6.