Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJP16K)

Drug Name
Bicyclic pyrimidine derivative 2 Drug Info
Synonyms PMID27718763-Compound-4
Cross-matching ID
PubChem CID
76853231
TTD Drug ID
DMJP16K

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Platelet-activating factor acetylhydrolase (PLA2G7) TTDNFMT PAFA_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Platelet-activating factor acetylhydrolase (PLA2G7) DTT PLA2G7 5.609 5.198 3.818 4.385
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Platelet-activating factor acetylhydrolase (PLA2G7) DTT PLA2G7 5.33E-03 0.09 0.23
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Inhibitors of phospholipase A2 and their therapeutic potential: an update on patents (2012-2016).Expert Opin Ther Pat. 2017 Feb;27(2):217-225.