General Information of Drug (ID: DMJP5YH)

Drug Name
4-(dimethylamino)-N-(thiazol-2-yl)benzamide Drug Info
Synonyms 4-(dimethylamino)-N-(1,3-thiazol-2-yl)benzamide; AC1M7A6S; CHEMBL425124; MolPort-004-070-500; ZINC3346941; AKOS017059191; MCULE-5265697892; N-(Thiazole-2-yl)-4-(dimethylamino)benzamide; Z28173761
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2463677
TTD Drug ID
DMJP5YH

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
LOX-5 messenger RNA (ALOX5 mRNA) TTSJ6Q4 LOX5_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
LOX-5 messenger RNA (ALOX5 mRNA) DTT ALOX5 4.966 5.133 5.358 6.128
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
LOX-5 messenger RNA (ALOX5 mRNA) DTT ALOX5 9.43E-03 0.14 0.28
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening. J Med Chem. 2007 May 31;50(11):2640-6.