Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJPD06)

• Drug Name: Lmw heparin Drug Info
• Synonyms: Fragmin; Heparinin; MolPort-042-652-620; Logiparin (TN); Sandoparin (TN)

Indication

Disease Entry	ICD 11	Status	REF
Coagulation defect	3B10.0	Approved	[1]
Hematologic disease	3C0Z	Approved	[1]

• Cross-matching ID:
  PubChem CID: 25244225
  TTD Drug ID: DMJPD06

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Coagulation factor Xa (F10)	TTCIHJA	FA10_HUMAN	Modulator	[2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Coagulation factor Xa (F10)	DTT	F10	7.763	4.672	3.248	4.609

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Coagulation defect
• ICD Disease Classification: 3B10.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Coagulation factor Xa (F10)	DTT	F10	4.84E-02	-0.28	-0.9

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [2] Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.