Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMK1IMC)

Drug Name
ANG-2004 Drug Info
Synonyms ANG-Leptin; EPiC-peptide conjugated leptin (obesity), AngioChem
Indication
Disease Entry ICD 11 Status REF
Obesity 5B81 Investigative [1]
Cross-matching ID
TTD Drug ID
DMK1IMC

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leptin receptor (LEPR) TT0HD6V LEPR_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Leptin receptor (LEPR) DTT LEPR 8.131 5.561 5.776 5.3
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Obesity
ICD Disease Classification 5B81
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Leptin receptor (LEPR) DTT LEPR 5.82E-02 0.05 0.15
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).