Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMKMTR7)

Drug Name
LDI-200 Drug Info
Synonyms Chorionic gonadotropin, Milkhaus; HCG, Milkhaus; Oncology therapeutics, Milkhaus
Indication
Disease Entry ICD 11 Status REF
leukaemia 2A60-2B33 Discontinued in Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMKMTR7

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Luteinizing hormone receptor (LHCGR) TT2O4W9 LSHR_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Luteinizing hormone receptor (LHCGR) DTT LHCGR 4.009 2.561 3.365 4.828
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease leukaemia
ICD Disease Classification 2A60-2B33
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Luteinizing hormone receptor (LHCGR) DTT LHCGR 3.55E-01 5.41E-04 4.54E-03
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006739)
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254).