Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMKWB73)

Drug Name

Epoetin alfa Drug Info

Synonyms

Epogen (TN); Procrit (TN)

Indication

Disease Entry	ICD 11	Status	REF
Anemia	3A00-3A9Z	Approved	[1]

Therapeutic Class

Antianemic Agents

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Erythropoietin Receptor (EPOR)	TTAUX24	EPOR_HUMAN	Agonist	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Erythropoietin Receptor (EPOR)	DTT	EPOR	5.166	4.594	4.469	4.763

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Anemia

ICD Disease Classification

3A00-3A9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Erythropoietin Receptor (EPOR)	DTT	EPOR	7.04E-01	0.11	0.27

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (BLA) 103951.
2	2007 Standards, Options, and Recommendations: use of erythropoiesis-stimulating agents (ESA: epoetin alfa, epoetin beta, and darbepoetin) for the management of anemia in children with cancer. PediatrBlood Cancer. 2009 Jul;53(1):7-12.