Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMKXRJ4)

Drug Name
US8889696, 39 Drug Info
Synonyms CHEMBL3702566; SCHEMBL13385799; BDBM139539; US8889696, 39
Cross-matching ID
PubChem CID
70895719
TTD Drug ID
DMKXRJ4

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Protein kinase C zeta (PRKCZ) TTUWGRA KPCZ_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Protein kinase C zeta (PRKCZ) DTT PRKCZ 3.935 6.204 5.503 7.245
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Protein kinase C zeta (PRKCZ) DTT PRKCZ 5.78E-42 0.75 0.9
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Substituted pyrido[2,3-d]pyrimidin-7(8H)-ones and therapeutic uses thereof. US8889696.