Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DML35GB)

Drug Name

N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE Drug Info

Synonyms

N~3~-(3-Pyridin-3-Ylbenzyl)pyridine-2,3-Diamine; 2ohr; SCHEMBL8264924; CHEMBL220346; BDBM15782; 3-Substituted 2-Aminopyridine 6a; ZINC10339547; DB07284; 3-N-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11701820
TTD Drug ID: DML35GB

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Beta-secretase (BACE)	TT8JRS7	NOUNIPROTAC	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Beta-secretase (BACE)	DTT	BACE	5.928	4.638	6.443	5.3

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Beta-secretase (BACE)	DTT	NO-GeName	6.98E-04	1.03	2.84

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.