Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DML4JXZ)

Drug Name
F-7TG Drug Info
Synonyms Recombinant human factor VIIa (hemophilia), GTC/LFB; RhFVIIa (hemophilia), GTC/LFB
Indication
Disease Entry ICD 11 Status REF
Hemophilia 3B10.0 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DML4JXZ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor VII (F7) TTF0EGX FA7_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Coagulation factor VII (F7) DTT F7 9.218 4.853 5.6 5.747
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Hemophilia
ICD Disease Classification 3B10.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor VII (F7) DTT F7 2.52E-01 -0.03 -0.19
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 GTC BIOTHERAPEUTICS REPORTS THIRD QUARTER 2010 FINANCIAL RESULTS. U.S. Securities and Exchange Commission. October 27, 2010.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2363).