Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DML6TAS)

Drug Name
OPI-1002 Drug Info
Indication
Disease Entry ICD 11 Status REF
Acute kidney injury GB60 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DML6TAS

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
P53 messenger RNA (TP53 mRNA) TT12KOD P53_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
P53 messenger RNA (TP53 mRNA) DTT TP53 5.257 4.938 5.396 5.626
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Acute kidney injury
ICD Disease Classification GB60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
P53 messenger RNA (TP53 mRNA) DTT TP53 7.90E-07 0.3 0.59
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 2011 Pipeline of Quark Pharm.