Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMLO0KD)

• Drug Name: Vicineum Drug Info
• Synonyms: Oportuzumab monatox

Indication

Disease Entry	ICD 11	Status	REF
Bladder cancer	2C94	Phase 3	[1]

• Cross-matching ID: TTD Drug ID: DMLO0KD

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tumor-associated calcium signal transducer 1 (EPCAM)	TTZ8WH4	EPCAM_HUMAN	Not Available	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tumor-associated calcium signal transducer 1 (EPCAM)	DTT	EPCAM	4.307	10.904	9.628	10.804

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Bladder cancer
• ICD Disease Classification: 2C94

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tumor-associated calcium signal transducer 1 (EPCAM)	DTT	EPCAM	5.99E-02	-0.11	-1.11

References

• [1] Clinical pipeline report, company report or official report of Sesen Bio.