Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMMAUOK)

Drug Name
PEN-221 Drug Info
Indication
Disease Entry ICD 11 Status REF
Neuroendocrine cancer 2B72.1 Phase 1/2 [1]
Small-cell lung cancer 2C25.Y Phase 1/2 [1]
Cross-matching ID
PubChem CID
118634103
CAS Number
CAS 1853254-97-3
TTD Drug ID
DMMAUOK

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Somatostatin receptor type 2 (SSTR2) TTZ6T9E SSR2_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Somatostatin receptor type 2 (SSTR2) DTT SSTR2 4.703 4.931 5.624 5.184
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Neuroendocrine cancer
ICD Disease Classification 2B72.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Somatostatin receptor type 2 (SSTR2) DTT SSTR2 9.79E-07 -0.38 -0.65
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)