Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMMEPKR)

Drug Name
PEG-Interferon lambda (IL-29) Drug Info
Indication
Disease Entry ICD 11 Status REF
Virus infection 1A24-1D9Z Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMMEPKR

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-29 (IL29) TTM624L IFNL1_HUMAN Agonist [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Virus infection
ICD Disease Classification 1A24-1D9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin-29 (IL29) DTT IFNL1 4.97E-01 -0.01 -0.02
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT00565539) Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection. U.S. National Institutes of Health.
2 Preclinical and clinical development of pegylated interferon-lambda 1 in chronic hepatitis C. J Interferon Cytokine Res. 2010 Aug;30(8):591-5.