Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMMKOCL)

Drug Name
AMT-050 Drug Info
Synonyms ApoA1 deficiency gene therapy, Amsterdam Molecular Therapeutics
Indication
Disease Entry ICD 11 Status REF
Cholesterol metabolism disorder 5C8Z Terminated [1]
Cross-matching ID
TTD Drug ID
DMMKOCL

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Apolipoprotein A-I (APOA1) TT7GN3U APOA1_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Apolipoprotein A-I (APOA1) DTT APOA1 13.036 4.508 4.982 12.009
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Cholesterol metabolism disorder
ICD Disease Classification 5C8Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Apolipoprotein A-I (APOA1) DTT APOA1 8.72E-01 -0.03 -0.45
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026835)
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026835)