General Information of Drug (ID: DMMSI67)

Drug Name
2-(Phenylsulfonamido)acetic Acid Drug Info
Synonyms
2-(Phenylsulfonamido)acetic Acid; 5398-96-9; Benzenesulfonylamino-acetic acid; n-(phenylsulfonyl)glycine; 2-benzenesulfonamidoacetic acid; CHEMBL37054; 2-(benzenesulfonamido)acetic acid; 2-[(phenylsulfonyl)amino]acetic acid; n-benzenesulfonylglycine; N-benzenesulfonyl-glycine; ChemDiv3_006100; CBChromo1_000178; AC1Q6W5M; Oprea1_227014; Oprea1_645532; CBDivE_002981; SCHEMBL359770; AC1Q763K; NSC3682; MolPort-000-182-647; WTSZSAHZIMPSDM-UHFFFAOYSA-N; ZINC187388; HMS1490F06; NSC-3682; AC1L5954; NSC121986; STL477593; SBB015317
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
220662
CAS Number
CAS 5398-96-9
TTD Drug ID
DMMSI67

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aldose reductase (AKR1B1) TTFBNVI ALDR_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Aldose reductase (AKR1B1) DTT AKR1B1 7.436 8.652 9.874 8.066
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Aldose reductase (AKR1B1) DTT AKR1B1 1.08E-20 0.94 1.58
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activ... J Med Chem. 2010 Nov 11;53(21):7756-66.