Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMMU2BZ)

Drug Name

2-(4-aminophenylsulfonamido)acetic acid Drug Info

Synonyms

5616-30-8; (4-Amino-benzenesulfonylamino)-acetic acid; 2-(4-aminophenylsulfonamido)acetic acid; 2-[(4-aminophenyl)sulfonylamino]acetic acid; CHEMBL285053; (4-aminophenylsulfonylamino)acetic acid; Glycine, N-[(4-aminophenyl)sulfonyl]-; 2-(4-aminobenzenesulfonylamino)ethanoic acid; Sulfanilamidoacetic acid; 2-(4-aminophenylsulfonamido)aceticacid; AC1L92ZE; SCHEMBL1228868; N-4-aminobenzenesulfonyl glycine; CTK1F5176; DTXSID30328582; ((4-aminophenyl)sulfonyl)glycine; BPJUMYMTQYMSFZ-UHFFFAOYSA-N; ZINC1670307

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 412201
CAS Number: CAS 5616-30-8
TTD Drug ID: DMMU2BZ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aldose reductase (AKR1B1)	TTFBNVI	ALDR_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aldose reductase (AKR1B1)	DTT	AKR1B1	7.436	8.652	9.874	8.066

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aldose reductase (AKR1B1)	DTT	AKR1B1	1.08E-20	0.94	1.58

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors. Bioorg Med Chem. 2008 Apr 1;16(7):3926-32.