Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMMYLTI)

Drug Name
Thyrotropin Alfa Drug Info
Indication
Disease Entry ICD 11 Status REF
Thyroid cancer 2D10 Approved [1]
Therapeutic Class
Diagnostic Agents
Cross-matching ID
PubChem CID
32281
TTD Drug ID
DMMYLTI

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thyrotropin receptor (TSHR) TT6NYJA TSHR_HUMAN Binder [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Thyrotropin receptor (TSHR) DTT TSHR 2.036 2.406 0.848 2.585
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Thyroid
The Studied Disease Thyroid cancer [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Thyrotropin receptor (TSHR) DTT TSHR 9.30E-18 -0.72 -1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020898.
2 Pharmacological profiles and clinical effects of recombinant human thyrotropin alfa (Thyrogen) Intramuscular Injection 0.9 mg). Nippon Yakurigaku Zasshi. 2009 Jul;134(1):28-34.