Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN0S1G)

• Drug Name: HEGF Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Diabetic foot ulcer	BD54	Approved	[1]

• Cross-matching ID: TTD Drug ID: DMN0S1G

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Epidermal growth factor receptor (EGFR)	TTGKNB4	EGFR_HUMAN	Activator	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Epidermal growth factor receptor (EGFR)	DTT	EGFR	6.045	4.991	5.317	5.252

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Diabetic foot ulcer
• ICD Disease Classification: BD54

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Epidermal growth factor receptor (EGFR)	DTT	EGFR	5.84E-05	0.32	0.55

References

• [1] Emerging drugs for diabetic foot ulcers. Expert Opin Emerg Drugs. 2006 Nov;11(4):709-24.