General Information of Drug (ID: DMN6IV2)

Drug Name
2-(2-benzhydryl-4-phenylthiazol-5-yl)acetic acid Drug Info
Synonyms CHEMBL603459; 2-(2-benzhydryl-4-phenylthiazol-5-yl)acetic acid; SCHEMBL5056681; BDBM50309282
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
46230226
TTD Drug ID
DMN6IV2

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin D2 receptor 2 (PTGDR2) TTQDMX5 PD2R2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Prostaglandin D2 receptor 2 (PTGDR2) DTT PTGDR2 4.436 5.954 4.217 4.641
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostaglandin D2 receptor 2 (PTGDR2) DTT PTGDR2 6.11E-02 -0.15 -0.25
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1181-5.