Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN97TC)

Drug Name

4-(2-(4-chlorobenzyloxy)-5-bromobenzyl)morpholine Drug Info

Synonyms

CHEMBL391379; Morpholine, 4-[[5-bromo-2-[(4-chlorophenyl)methoxy]phenyl]methyl]-; 851546-84-4; 4-(2-(4-chlorobenzyloxy)-5-bromobenzyl)morpholine; SCHEMBL5699765; CTK3C9230; DTXSID80458181; 4-[[5-bromo-2-[(4-chlorophenyl)methoxy]phenyl]methyl]morpholine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11188669
CAS Number: CAS 851546-84-4
TTD Drug ID: DMN97TC

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
C-C chemokine receptor type 5 (CCR5)	TT2CEJG	CCR5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
C-C chemokine receptor type 5 (CCR5)	DTT	CCR5	9.30E-01	-0.08	-0.11

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	CCR5 receptor antagonists: discovery and SAR study of guanylhydrazone derivatives. Bioorg Med Chem Lett. 2007 Jan 1;17(1):231-4.