Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNEY58)

Drug Name
ML272 Drug Info
Synonyms
N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide; CHEMBL492797; 1130067-18-3; ML272; VU0155056-2; SCHEMBL2724877; BDBM87245; cid_53481919; CHEBI:131157; NCGC00386898-01; VU0155056-3; VU0155056-1; US9453017, 3; VU0156056 (1); N-[2-[4-(2-keto-3H-benzimidazol-1-yl)piperidino]ethyl]-2-naphthamide;hydrochloride; N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide;hydrochloride; N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide
Cross-matching ID
PubChem CID
25105704
ChEBI ID
CHEBI:131157
TTD Drug ID
DMNEY58

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phospholipase D1 (PLD1) TT3T17P PLD1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Phospholipase D1 (PLD1) DTT PLD1 5.358 5.213 5.027 6.159
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Phospholipase D1 (PLD1) DTT PLD1 7.36E-01 0.08 0.15
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Antiviral therapies with phospholipase D inhibitors. US9453017.