Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNFDYE)

Drug Name
KD3010 Drug Info
Indication
Disease Entry ICD 11 Status REF
Metabolic disorder 5C50-5D2Z Phase 1 [1]
Obesity 5B81 Phase 1 [1]
Cross-matching ID
PubChem CID
75412604
TTD Drug ID
DMNFDYE

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Peroxisome proliferator-activated receptor delta (PPARD) TT2JWF6 PPARD_HUMAN Agonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Peroxisome proliferator-activated receptor delta (PPARD) DTT PPARD 4.883 5.664 3.897 3.678
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Metabolic disorder
ICD Disease Classification 5C50-5D2Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Peroxisome proliferator-activated receptor delta (PPARD) DTT PPARD 3.78E-01 9.87E-03 0.06
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Kalypsys nearing completion of phase Ia study of KD3010 for metabolic disorders. Kalypsys. 2007.