Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNFZYE)

Drug Name
WT1-targeted autologous dendritic cell vaccine Drug Info
Synonyms WT1-targeted autologous dendritic cell vaccine (cancer)
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMNFZYE

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Wilms tumor protein (WT1) TTZ8UT4 WT1_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Wilms tumor protein (WT1) DTT WT1 3.256 2.655 5.113 2.963
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Acute myeloid leukaemia
ICD Disease Classification 2A60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Wilms tumor protein (WT1) DTT WT1 5.12E-79 1.54 7.84
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT01686334) Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission. U.S. National Institutes of Health.