Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNUO79)

Drug Name
(1-Amino-3-methyl-butyl)-phosphinic acid Drug Info
Synonyms AC1O4HVH; Phosphinic acid, P-(1-amino-3-methylbutyl)-; SCHEMBL5037193; 80744-65-6
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
54361028
TTD Drug ID
DMNUO79

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aminopeptidase N (ANPEP) TTPHMWB AMPN_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Aminopeptidase N (ANPEP) DTT ANPEP 8.744 7.809 8.914 11.49
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Aminopeptidase N (ANPEP) DTT ANPEP 8.84E-07 -0.3 -0.71
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1511-6.