Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNX6CE)

Drug Name

1-(2,2'-bithiophen-5-yl)methanamine Drug Info

Synonyms

4380-96-5; [2,2'-Bithiophen]-5-ylmethanamine; 2,2'-bithiophene-5-methylamine; 2,2'-bithiophen-5-ylmethanamine; [2,2'-Bithiophene]-5-methanamine; 1-(2,2'-bithiophen-5-yl)methanamine; 2,2-Bithiophene-5-methylamine; CHEMBL538940; (5-(2-thienyl)-2-thienyl)methylamine; [5-(Thiophen-2-Yl)Thiophen-2-Yl]Methanamine; SDCCGMLS-0065983.P001; AC1MCQYM; SCHEMBL2690127; CTK1D7717; DTXSID50380066; MolPort-000-142-515; FHYTVXBZSXZMGD-UHFFFAOYSA-N; ZINC158800; 2,2''-bithiophen-5-ylmethanamine; AC1Q5409; QC-966; SBB091920; BDBM50294164

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2776424
CAS Number: CAS 4380-96-5
TTD Drug ID: DMNX6CE

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leukotriene A-4 hydrolase (LTA4H)	TTXZEAJ	LKHA4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	7.338	7.827	8.134	8.612

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	1.31E-48	-1.22	-2.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.