Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMO0CA8)

Drug Name
SHP616 Drug Info
Indication
Disease Entry ICD 11 Status REF
Neuromyelitis optica 8A43 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMO0CA8

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement C1s component (C1S) TT7LRQH C1S_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Complement C1s component (C1S) DTT C1S 12.194 10.051 9.335 8.798
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Neuromyelitis optica
ICD Disease Classification 8A43
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement C1s component (C1S) DTT C1S 5.50E-01 1.09 0.91
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)