Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMO7TES)

Drug Name

CCX507 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Ulcerative colitis	DD71	Phase 1	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
C-C chemokine receptor type 9 (CCR9)	TTIPS8B	CCR9_HUMAN	Antagonist	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
C-C chemokine receptor type 9 (CCR9)	DTT	CCR9	5.109	5.146	5.603	6.888

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Ulcerative colitis

ICD Disease Classification

DD71

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
C-C chemokine receptor type 9 (CCR9)	DTT	CCR9	7.74E-01	0.02	0.22

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)