Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMOGZLU)

• Drug Name: LLZ16406 Drug Info
• Synonyms: hydrogen chloride; Muriatic acid; 7647-01-0; Chlorohydric acid; Acide chlorhydrique; Chlorwasserstoff; Spirits of salt; Hydrogen chloride (HCl); chlorane; Chlorowodor; Chloorwaterstof; Anhydrous hydrochloric acid; Bowl Cleaner; Acido cloridrico; Aqueous hydrogen chloride; chlorure d'hydrogene; Hydrochloric acid gas; 4-D Bowl Sanitizer; Chlorowodor [Polish]; Emulsion Bowl Cleaner; Caswell No. 486; Chloorwaterstof [Dutch]; Marine acid; Hydrochloric acid [JAN]; Spirit of salt; Chlorwasserstoff [German]; UN 1789 (solut

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID: TTD Drug ID: DMOGZLU

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
MAPK/ERK kinase kinase 1 (MAP3K1)	TTQBCEJ	M3K1_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
MAPK/ERK kinase kinase 1 (MAP3K1)	DTT	MAP3K1	1.379	2.485	4.392	1.322

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
MAPK/ERK kinase kinase 1 (MAP3K1)	DTT	MAP3K1	6.07E-03	-0.28	-0.52

References

• [1] Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci. 2002 Jan;23(1):40-5.