Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMOS68D)

Drug Name

(4-fluorophenyl)(pyridin-4-yl)methanone Drug Info

Synonyms

4-(4-Fluorobenzoyl)pyridine; 41538-36-7; (4-fluorophenyl)(pyridin-4-yl)methanone; Methanone, (4-fluorophenyl)-4-pyridinyl-; CHEMBL563196; 4-fluorophenyl 4-pyridyl ketone; (4-fluorophenyl)-pyridin-4-ylmethanone; AC1ODYVS; 3fu0; ACMC-20amw5; AC1Q4LVT; SCHEMBL4618020; CTK1D3778; DTXSID60427471; MolPort-001-628-204; WTRWBYGUMQEFFI-UHFFFAOYSA-N; ZINC2583439; (4-Pyridyl)(p-fluorophenyl) ketone; BDBM50294173; MFCD02683088; SBB092751; 4-[(4-fluorophenyl)carbonyl]pyridine; AKOS003603273; MCULE-1391167832; DB06917; NE40002

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 7023019
CAS Number: CAS 41538-36-7
TTD Drug ID: DMOS68D

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leukotriene A-4 hydrolase (LTA4H)	TTXZEAJ	LKHA4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	7.338	7.827	8.134	8.612

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	1.31E-48	-1.22	-2.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.