Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMOS864)

• Drug Name: (2-chloro-6-phenoxyphenyl)methanamine Drug Info
• Synonyms: 2-Chloro-6-phenoxybenzylamine; 175136-89-7; (2-chloro-6-phenoxyphenyl)methanamine; CHEMBL203105; AC1MCRJE; rarechem al bw 1398; SCHEMBL112755; AC1Q53T0; 2-chloro-6-phenoxy-benzylamine; CTK4D5311; DTXSID20380412; SNTOZVXKDWQFEW-UHFFFAOYSA-N; MolPort-000-144-285; ZINC159665; ZX-AT024720; 2-aminomethyl-3-chlorodiphenylether; SBB098143; BDBM50178429; (6-chloro-2-phenoxyphenyl)methylamine; 2-chloro-6-phenoxybenzylamine, 95+%; AKOS009159323; Benzenemethanamine,2-chloro-6-phenoxy-; KB-68526; SC-40136; AJ-15516; ACM175136897; DB-030613

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 2777206
  CAS Number: CAS 175136-89-7
  TTD Drug ID: DMOS864

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Dipeptidyl peptidase 4 (DPP-4)	TTDIGC1	DPP4_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Dipeptidyl peptidase 4 (DPP-4)	DTT	DPP4	4.995	4.926	7.852	8.358

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Dipeptidyl peptidase 4 (DPP-4)	DTT	DPP4	9.54E-01	-0.27	-1.85

References

• [1] In silico fragment-based discovery of DPP-IV S1 pocket binders. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1405-9.