Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMP3YTE)

Drug Name
Inclisiran Drug Info
Indication
Disease Entry ICD 11 Status REF
Familial hypercholesterolemia 5C80.00 Approved [1]
Hypercholesterolaemia 5C80.0 Phase 3 [2]
Cross-matching ID
PubChem CID
126480325
TTD Drug ID
DMP3YTE

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PCSK9 messenger RNA (PCSK9 mRNA) TTNIZ2B PCSK9_HUMAN Not Available [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 05 Endocrine, nutritional or metabolic disease
Disease Class ICD-11: 5A11 Type 2 diabetes mellitus
The Studied Tissue Whole blood
The Studied Disease Familial hypercholesterolemia [ICD-11:5A11]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PCSK9 messenger RNA (PCSK9 mRNA) DTT PCSK9 4.82E-02 -0.07 -0.3
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 FDA Approved Drug Products from FDA Official Website. 2021. Application Number: 214012.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)