Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMP8O6R)

Drug Name

L-Thiocitrulline Drug Info

Synonyms

L-thiocitrulline; (S)-2-Amino-5-(thioureido)pentanoic acid; CHEMBL93247; SCI; (2S)-2-amino-5-[(aminothioxomethyl)amino]pentanoic acid; AC1MBZ2U; KBioGR_000498; BSPBio_001158; KBioSS_000498; SCHEMBL156220; KBio3_000915; KBio2_005634; KBio2_003066; KBio2_000498; KBio3_000916; Thio-L-citrulline, > BKGWACHYAMTLAF-BYPYZUCNSA-N; HMS3403J19; HMS1990J19; Bio1_000374; HMS1362J19; Bio2_000899; HMS1792J19; Bio2_000419; Bio1_001352; Bio1_000863

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2733514
CAS Number: CAS 156719-37-8
TTD Drug ID: DMP8O6R

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nitric-oxide synthase inducible (NOS2)	TTF10I9	NOS2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Nitric-oxide synthase inducible (NOS2)	DTT	NOS2	4.95	5.198	4.573	5.121

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nitric-oxide synthase inducible (NOS2)	DTT	NOS2	4.24E-02	-0.27	-0.88

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.