Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPQKGY)

Drug Name

4-methoxy-N-(thiazol-2-yl)benzamide Drug Info

Synonyms

4-Methoxy-N-thiazol-2-yl-benzamide; 4-methoxy-N-1,3-thiazol-2-ylbenzamide; 4-methoxy-benzoic acid thiazol-2-ylamide; 4-methoxy-N-(1,3-thiazol-2-yl)benzamide; 303122-55-6; BAS 00626024; Oprea1_481467; Oprea1_830630; MLS001209223; ARONIS023447; CHEMBL387618; AC1Q49Y5; AC1LF170; MolPort-001-004-838; ZINC123532; HMS2848F19; STK031490; AKOS001320075; MCULE-9448418356; KS-0000469Q; ST089107; SMR000514833; KB-115289; 4-methoxy-N~1~-(1,3-thiazol-2-yl)benzamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 721308
TTD Drug ID: DMPQKGY

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
LOX-5 messenger RNA (ALOX5 mRNA)	TTSJ6Q4	LOX5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
LOX-5 messenger RNA (ALOX5 mRNA)	DTT	ALOX5	4.966	5.133	5.358	6.128

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
LOX-5 messenger RNA (ALOX5 mRNA)	DTT	ALOX5	9.43E-03	0.14	0.28

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening. J Med Chem. 2007 May 31;50(11):2640-6.