Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMQ1D9A)

• Drug Name: 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID Drug Info
• Synonyms: 5731-10-2; 4-(4-Fluorophenyl)benzoic acid; 4'-Fluoro-biphenyl-4-carboxylic acid; 4'-fluorobiphenyl-4-carboxylic acid; 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID; 4'-Fluoro-biphenyl-4-carboxylic aci; 4'-Fluoro-[1,1'-biphenyl]-4-carboxylic acid; CHEMBL106708; MFCD01631909; 4-(4-Fluorophenyl)benzoic acid, 97%; 4'-fluoro[1,1'-biphenyl]-4-carboxylic acid; 4FC; 4'-fluoro(1,1'-biphenyl)-4-carboxylic acid; 1ysg; 4-Biphenyl-4'-fluoro-carboxylicacid; 4-Biphenyl-4'-fluoro-carboxylic acid; PubChem10277; 1,5-dibenzoyloxybenzene

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 2782689
  CAS Number: CAS 5731-10-2
  TTD Drug ID: DMQ1D9A

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Apoptosis regulator Bcl-xL (BCL-xL)	TTU1E82	B2CL1_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Apoptosis regulator Bcl-xL (BCL-xL)	DTT	BCL2L1	4.863	5.664	6.092	5.843

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Apoptosis regulator Bcl-xL (BCL-xL)	DTT	BCL2L1	7.28E-13	-0.55	-0.68

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.